APPLICATIONS AND IMPACT
IMAS (highly sensitive molecular imaging) will open-up new venues in diagnostic imaging enabling several medical imaging breakthroughs:
· IMAGING BABIES
· DYNAMIC AND SIMULTANEOUS
· STUDIES OF SEVERAL ORGANS
· IMAGING LONGER AND FASTER
· IMAGING TUMOR HETEROGENEITY
· NON-MALIGNANT DISEASES IMAGING
•Total body images in < 1 min
- Respiration effect reduced
- Kinematics of the whole body with high timing resolution
- Higher patients throughput
LONGER DYNAMIC RANGE/BETTER SNR
Due to the high dynamic PET range, possible to acquire images around 3-5 times longer the positrons emitters half-life. For 11C or 18F, it will be possible to extend to 2-3 or 16-18 hours.
Better SNR, factor 2-3
Improved reconstructed image quality
Detection of low active lesions
Detection of small lesions
Better statistics as for kinetic modelling
PET AND CT IMAGING TIME
Practice and scanner performances vary widely but 10 min / 100 cm seems to be a reasonable market average for FDG.
Few aggressive center can push it to -6-8 min, many lower sensitivity scanners can use up to 20 min.
Brain and Heart imaging are also at around 10-15 min for most scanner
No expectation of faster scans
Singles sensitivity already very high.
Dose reduction to the patient would force lower the injected dose, making longer scans possible
Range of applications and imaging time much wider than PET
Current whole-body CT part of PET/CT in the order of 10-30 sec / 100 cm
Except for very wide area CT, few scans require only one fix scan
Expectation of faster scans in the future with faster rotation CT to accommodate more patients
Typically, CT is at least 10-20 times faster than PET